Perry Greenfield got his Ph.D. in Physics from M.I.T. in Radio Astronomy studying the first discovered gravitational lens with the Very Large Array. He has been at the Space Telescope Science Institute for 36 years and is currently a Consulting Science Software Engineer. He and his group started using Python in 1998 and pioneered the use of Python in astronomy, being involved in key developments such as PyRAF, pyfits, numarray, matplotlib, and Astropy. Python plays a central role in the science software for the Hubble and James Webb Space Telescopes, and the future Nancy Grace Roman Space Telescope.